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by Tissue Type by Application

Lung ECM cell culture substrates

Extracellular matrix (ECM) is a major component of the cell microenvironment with important signaling and regulatory functions. Derived from healthy acellular porcine lung, TissueSpec® lung matrix is rich in basement membrane proteins including collagen IV and laminins, sulfated glycosaminoglycans (e.g., heparin sulfate), and structural collagen I and elastin fibers that provide crucial biomechanical signaling for pulmonary airway and alveolar cell types.

TissueSpec® Lung Scaffolds supported enhanced proliferation, expression of alveolar epithelial cell markers, and re-uptake of surfactant by lung stem cells.

 

Item: MTSLG101 TissueSpec® ECM Hydrogel  Instructions Datasheet
Item: MTSLG201 NativeCoat™ ECM Surface Coating  Instructions Datasheet
Item: MTHNLG201 Human Normal NativeCoat™ ECM Coating Instructions  
Item: MTHDLG201 Human Diseased NativeCoat™ ECM Coating Instructions
Item: MTHNLG300 Human Normal TissueSpec® ECM Scaffold (custom) 
Item: MTHDLG300 Human Diseased TissueSpec® ECM Scaffold (custom)

 

Available Lines

Item #Product Name
MTSLG101 TissueSpec® Lung ECM Hydrogel MTSLG101 TissueSpec® Lung ECM Hydrogel Applications Instructions Datasheet
MTSLG201 NativeCoat™ Lung ECM Surface Coating MTSLG201 NativeCoat™ Lung ECM Surface Coating Applications Instructions Datasheet
MTHNLG201 Human Normal NativeCoat™ Lung ECM Coating MTHNLG201 Human Normal NativeCoat™ Lung ECM Coating Applications Instructions
MTHDLG201 Human Diseased NativeCoat™ Lung ECM Coating MTHDLG201 Human Diseased NativeCoat™ Lung ECM Coating Applications Instructions
MTHNLG300 Human Normal TissueSpec® Lung ECM Scaffold (custom) MTHNLG300 Human Normal TissueSpec® Lung ECM Scaffold (custom) Applications
MTHDLG300 Human Diseased TissueSpec® Lung ECM Scaffold (custom) MTHDLG300 Human Diseased TissueSpec® Lung ECM Scaffold (custom) Applications


Contact us to discuss your application and pricing options.
To make purchases outside the USA, click here.

Custom Matrix Formats

TissueSpec® ECM scaffolds are available through custom order. Xylyx Bio also specializes in isolating extracellular matrix from additional tissues or specific regions within tissues of interest as well as other sources (e.g., human).

Related Resources

Poster: TissueSpec® Extracellular Matrix Substrates for 3D Cell Culture
White paper: 3D lung tumor model with lung extracellular matrix to predict drug efficacy
Application note: Accelerating anti-fibrotic drug development with human fibrotic lung ECM substrates
Fibrotic Human Lung Extracellular Matrix as a Disease-Specific Substrate for Models of Pulmonary Fibrosis
Webinar: Transforming lung fibrosis drug discovery with the IN MATRICO® Human Lung Fibrosis platform

Products
BY TISSUE TYPE

Choose your tissue-specific ECM substrate based on the tissue and organ of origin.

Products
BY APPLICATION

Whether you work in drug development, cancer research, 3D models, or other areas, choose the right product for you based on your research area.