Cell Culture

Cartilage ECM cell culture substrates

Extracellular matrix (ECM) is a major component of the cell microenvironment with important signaling and regulatory functions. Derived from healthy acellular porcine hyaline cartilage, TissueSpec® cartilage matrix is rich in type II collagen with fibrous proteins, proteoglycans, hyaluronic acid (HA), and chondroitin sulfate that together regulate chondrogenesis, chondrocyte differentiation, response to mechanical stimulation, matrix remodeling, metabolism, and survival and provide biomechanical signals through cell-matrix interactions.

TissueSpec® Cartilage Hydrogels supported the chondrogenic differentiation of mesenchymal stem cells, which formed cartilageous tissue constructs and demonstrated increased mechanical stiffness and biochemical properties resembling native articular cartilage.

Item: MTSCT201
NativeCoat™ ECM Surface Coating 
Instructions Datasheet
Item: MTSCT300 TissueSpec® ECM Scaffold (custom) Datasheet


Tissue-Specific ECM Substrates

Extracellular matrix hydrogel and surface coating cell culture kits.

Contact us to discuss your application and pricing options.
To make purchases outside the USA, click here.

Custom ECM Formats

TissueSpec® ECM scaffolds are available through custom order. Xylyx Bio also specializes in isolating extracellular matrix from additional tissues or specific regions within tissues of interest as well as from other sources (e.g., human).

Other Culture Products

3D ECM Hydrogels

Culture your cells on the surface or within our cell-specific TissueSpec® ECM hydrogels to bring the complete, endogenous ECM environment into your in vitro setting.