by Tissue Type by Application

Bone ECM cell culture substrates

Extracellular matrix (ECM) is a major component of the cell microenvironment with important signaling and regulatory functions. Derived from healthy acellular porcine bone, TissueSpec® bone matrix is a network rich in collagen types I and III and other carboxylated proteins that contribute to bone mechanics, mineral nucleation, and osteocytogenesis.

Item: MTSBN101 TissueSpec® ECM Hydrogel  Instructions Datasheet
Item: MTSBN201
NativeCoat™ ECM Surface Coating  
Instructions Datasheet
Item: MTSBN300 TissueSpec® ECM Scaffold (custom) Datasheet


Available Lines

Item #Product Name
MTSBN101 TissueSpec® Bone ECM Hydrogel MTSBN101 TissueSpec® Bone ECM Hydrogel Applications Instructions Datasheet
MTSBN201 NativeCoat™ Bone ECM Surface Coating MTSBN201 NativeCoat™ Bone ECM Surface Coating Applications Instructions Datasheet
MTSBN300 TissueSpec® Bone ECM Scaffold (custom) MTSBN300 TissueSpec® Bone ECM Scaffold (custom) Datasheet

Contact us to discuss your application and pricing options.
To make purchases outside the USA, click here.

Custom Matrix Formats

TissueSpec® ECM scaffolds are available through custom order. Xylyx Bio also specializes in isolating extracellular matrix from additional tissues or specific regions within tissues of interest as well as other sources (e.g., human).

Related Resources

Application note: IN SITE™ Metastasis Kit to accelerate anticancer drug development
Poster: TissueSpec® Bone, Liver, and Lung ECM substrates enable disease-relevant in-vitro models of pre-metastatic tissue microenvironments.
Poster: TissueSpec® ECM Hydrogels for predictive 3D models of human cancer
Tissue Engineered Autologous Grafts for Facial Bone Reconstruction. Sci Transl Med. (2016)


Choose your tissue-specific ECM substrate based on the tissue and organ of origin.


Whether you work in drug development, cancer research, 3D models, or other areas, choose the right product for you based on your research area.