Kidney ECM cell culture substrates

Extracellular matrix (ECM) is a major component of the cell microenvironment with important signaling and regulatory functions. Derived from healthy acellular porcine kidney, TissueSpec® kidney matrix is rich in basement membrane proteins including collagen IV, laminins, and fibronectin and regulates key pathways in kidney development – including ureteric bud branching morphogenesis, renal tubule differentiation, glomerular assembly, and nephron formation – as well as in kidney repair and disease.

TissueSpec® Kidney Scaffolds signaled kidney stem cell formation of renal tubule structures similar to those in the renal medulla.